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DURATIA-60

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Characteristics

ACTIVE HALF-LIFE
15-18 hours
Classification
SSRI inhibitor
Dosage
Men 30-60 mg/day
ACNE
No
WATER RETENTION
Possible
HBR
No
HEPATOTOXICITY
No
AROMATIZATION
No
Active Substance
FORM
10 pills x 60 mg

Description

 

  • Chemical name: (1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine
  • Formula: C21H23NO
  • Anabolic activity index: not a steroid
  • Androgenic activity index: not a steroid

 

 

DURATIA-60 - FORTUNE HEALTHCARE

 

Duratia-60, manufactured by Fortune Healthcare, is a drug that can help treat premature ejaculation. It contains 60mg of the active ingredient Dapoxetine. Dapoxetine is an antidepressant drug that has been found to be effective in treating premature ejaculation. This drug is a selective serotonin reuptake inhibitor that works by increasing the levels of serotonin in body. Low levels of serotonin results in poor control over ejaculation. The drug increases serotonin levels and activity to help improve control over ejaculation and increases the time it takes to ejaculate.

Dosage

The recommended dose of Dapoxetine is 60mg. A physician may adjust the dose depending on the patient’s response and tolerance to the drug. A tablet of Duratia-60 must be taken orally, 1 to 3 hours before an anticipated sexual activity. The tablet must be swallowed whole to avoid the tablet’s bitter taste, with a glass of water. It may be taken with or without food. This medicine must be taken only once every 24 hours as needed. It is not intended for daily use.

Duratia-60 should only be used by men aged 18 to 64 years.

Contraindications

Duratia is contraindicated to patients with known allergy to the active ingredient, Dapoxetine and any of the tablet’s inactive ingredients. This medication is also contraindicated to patients with the following medical conditions:

  • Heart problems like heart failure, angina, heart valve problems
  • History of heart attack
  • History of fainting
  • History of bipolar disorder, mania, hypomania, severe depression
  • Psychiatric problem such as schizophrenia
  • Uncontrolled epilepsy
  • Severe kidney impairment
  • Moderate to severe liver impairment

 

Duratia is contraindicated to patients taking the following medications:

  • Recreational drugs
  • Linezolid
  • Lithium
  • Monoamine oxidase inhibitors
  • SNRI and SSRI antidepressants
  • Tricyclic antidepressants
  • St. John’s wort
  • Tramadol
  • Tryptophan
  • Triptans for migraine

 

Side effects

  • Dizziness or lightheadedness
  • Headache
  • Feeling sick, sweaty or confused – which may also be signs that fainting may occur
  • Duratia may cause blood pressure to drop that may make one dizzy or faint.

 

These side effects may be avoided by taking the tablet with a glassful of water and standing up slowly from long periods of sitting or lying position. If the symptoms start to appear, sit or lie down until the symptoms pass. The drug must not be taken when dehydrated. Taking of Duratia must be stopped and medical help must be sought immediately if these symptoms occur:

  • Seizures
  • Faints when standing up
  • Changes in mood
  • Thoughts of suicide or harming one’s self

 

Other side effects associated with Duratia-60 include:

  • Anxiety, agitation, irritability
  • Difficulty sleeping
  • Difficulty concentrating
  • Reduced libido
  • Feeling tired or sleepy
  • Erectile dysfunction
  • Nasal congestion
  • Ringing in the ears
  • Blurred vision
  • Flushing
  • Tremor
  • Gastrointestinal disturbances

 

Rare side effects include:

  • Suddenly falling asleep
  • Urgent need in emptying bowel
  • Dizziness after exertion

 

Warnings and Precautions

Driving, operating hazardous machineries or doing any unsafe tasks must be avoided while taking this medication until it is known how the body reacts to the drug or how the drug affects performance. Duratia must be used in caution to patients with the following medical conditions:

  • Mild to moderate kidney impairment
  • Mild liver impairment
  • History of low blood pressure
  • Epilepsy
  • Erectile dysfunction
  • History of bleeding disorder or clotting problems
  • At risk or have high pressure in the eye
  • Dehydration due to diarrhea, vomiting, excessive sweating and other factors

 

Duratia may interact with the following medications. Caution must be observed.

  • Blood thinners such as warfarin
  • Alpha-blockers, nitrates, and some drugs for blood pressure and chest pain
  • Some antifungals
  • Non-steroidal anti-inflammatory drugs
  • Some HIV medications
  • Some antibiotics
  • Aprepitant
  • Medicines for mental health problems

 

Duratia and beverages

  • Drinking alcohol must be avoided while taking Duratia for it may worsen side effects such as dizziness, drowsiness, and difficulty in concentrating. It may also increase the risk of injury from fainting and from other side effects.
  • Caution is advised when consuming grapefruit and grapefruit juice as it mildly affects the absorption and clearance of Dapoxetine.

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