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discreet

BITIRON

Customer Reviews Shipping options
$32.00

Characteristics

Classification
Thyroid hormones
ACNE
No
WATER RETENTION
No
HBR
No
HEPATOTOXICITY
No
AROMATIZATION
No
FORM
100 pills x 50 mcg T4 & 12.5 mcg T3
Manufacturer

Description

Bitiron is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion. It is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in peripheral tissues. Administration of levothyroxine alone is sufficient for maintaining serum T4 and T3 levels in most patients and combination hormone replacement therapy generally offers no therapeutic advantage. In fact, administration of T3 may result in supratherapeutic levels of T3.

Indications:

May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic lymphocytic thyroiditis multinodular goiter, and in the management of thyroid cancer. May be used in conjunction with other antithyroid agents to treat thyrotoxicosis to prevent goitrogenesis and hypothyroidism. May also be used for differential diagnosis of suspected mild hyperthyroidism or thyroid gland autonomy.

Pharmacodynamics:

Thyroid hormone drugs are natural or synthetic preparations containing T4 or T3 or both. T4 and T3 are produced in the human thyroid gland by the iodination and coupling of the amino acid tyrosine. Liotrix is a synthetic preparation of T4 and T3 in a 4:1 weight-based ratio. These hormones enhance oxygen consumption by most tissues of the body and increase the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins. Thus, they exert a profound influence on every organ system in the body and are of particular importance in the development of the central nervous system.

Mechanism of action:

The hormones, T4 and T3, are tyrosine-based hormones produced by the thyroid gland. Iodine is an important component in their synthesis. The major secreted form of thyroid hormone is T4. T4 is converted T3, the more active thyroid hormone, by deiodinases in peripheral tissues. T3 acts in the body to increase basal metabolic rate, alter protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline). Thyroid hormones are essential for proper development and differentiation of all cells of the human body. T4 and T3 regulate protein, fat and carbohydrate metabolism to varying extents. The most pronounced effect of the hormones is in altering how human cells use energetic compounds. The thyroid hormone derivatives bind to the thyroid hormone receptors initially to initiate their downstream effects.

Customer Reviews


Showtime
05.07.2018
Rating: GOOD
Verified Purchase
Product came fairly quick no, problems.
FS5
30.05.2018
Rating: EXCELLENT
Verified Purchase
It was a short delay to get my complete order....due to my instant gratification expectations but I must admit Pharmacomstore actually split my order for my own protection....no other company does that for anything, so THANK YOU! I bought a basic trimming cycle to get rid of some fat before I try to beef up. It has been about 3 weeks and I am feeling the strength starting to kicking back in. Having used gear before back in the 90's and 00's, I can tell quality stuff from fake garbage or the old prohormone substitutes. I took a chance and ordered 2 other cycles and the second has arrived and without asking I recieved an extra gift, I just popped a pill, my wife is in for a tremendous suprise on a week day.... Thank again!!!
Blackbrown
24.05.2018
Rating: EXCELLENT
Verified Purchase
It took a little longer than I expected but I must give Pharmacom it due credit. They split my order to make sure that it was not seized. I have yet to see my results but having used this product before I can feel it taking effect. I look forward to trimming down...
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